What to Expect Before, During, and After Your Platelet Rich Plasma Treatment
Platelet Rich Plasma therapy has moved from professional athletes’ recovery rooms into medical spas across Northern Colorado. At 18 Spa in Loveland, we’ve watched this regenerative treatment gain traction—not because of hype, but because patients see measurable improvements in skin texture, hair density, and overall tissue quality when the protocol is followed correctly.
This guide walks you through the entire PRP process: what happens during your consultation, how the treatment unfolds, and what the days and weeks afterward actually look like. No surprises, no guesswork—just the practical information you need to decide if PRP fits your goals.
Understanding Platelet Rich Plasma: The Science in Plain Terms
PRP uses components from your own blood to stimulate collagen production and cellular repair. Here’s the simplified version:
A small blood draw (similar to routine lab work) is processed in a centrifuge to separate plasma rich in growth factors and platelets. That concentrated plasma is then reintroduced to treatment areas via micro-injections or microneedling. The growth factors signal your body to ramp up healing and regeneration in targeted zones—face, scalp, neck, or hands.
Because the substance comes from your own body, allergic reactions are extremely rare. The treatment works with your biology, not against it.
Pre-Treatment: How to Prepare for Optimal Results
Your preparation starts about two weeks before your appointment. These steps aren’t optional—they directly affect how well your platelets perform.
Two Weeks Before:
- Stop NSAIDs (ibuprofen, aspirin, naproxen)—they interfere with platelet function
- Avoid fish oil, vitamin E, and other blood-thinning supplements
- Limit alcohol consumption
- Stay well-hydrated (aim for 64+ ounces of water daily)
48 Hours Before:
- Skip retinoids and exfoliating acids on treatment areas
- Avoid intense sun exposure or tanning
- Do not wax or use depilatory creams on the target zone
Day of Treatment:
- Eat a full meal 1–2 hours before your appointment (low blood sugar can make the blood draw uncomfortable)
- Arrive with clean skin—no makeup, lotions, or serums
- Wear comfortable clothing; you may be reclined for 45–60 minutes
Your RN will review your health history and current medications during your consultation. Certain conditions (active infections, blood disorders, immunosuppression) may delay or disqualify you from PRP.
During Your Platelet Rich Plasma Session: Step-by-Step
Knowing the sequence helps ease first-timer nerves. Here’s what happens in the treatment room:
Step 1: Blood Draw (5 minutes)
A small vial of blood is collected from your arm—typically 10–20 mL, depending on the treatment area size.
Step 2: Centrifuge Processing (10–15 minutes)
Your blood spins in a medical-grade centrifuge to isolate the platelet-rich layer. You’ll rest during this phase.
Step 3: Numbing (10–15 minutes)
Topical anesthetic is applied to treatment areas. For scalp PRP, numbing is lighter; for facial microneedling with PRP, we allow more time for comfort.
Step 4: Application (20–30 minutes)
The concentrated plasma is delivered via fine needles (for injection-based PRP) or applied topically during microneedling passes. You’ll feel pressure and mild pricking—most patients describe it as tolerable, not painful.
Step 5: Post-Treatment Serum & Instructions (5 minutes)
We apply a soothing serum, review your aftercare sheet, and schedule your next session if you’re doing a series.
Total time in-office: 60–75 minutes.
Immediate Aftercare: The First 24–48 Hours
Your skin or scalp will look and feel different right after PRP. This is normal and temporary.
What You’ll Notice:
- Redness and mild swelling (like a moderate sunburn)
- Pinpoint bleeding or bruising at injection sites
- Tightness or tenderness in treated areas
- Possible mild headache if scalp was treated
What to Do:
- Keep the area clean and dry for 12 hours—no washing, sweating, or swimming
- Sleep with your head elevated on clean pillowcases
- Apply ice packs (wrapped in cloth) for 10 minutes at a time to reduce swelling
- Avoid touching, rubbing, or picking at the skin
What to Avoid:
- Makeup or skincare products for 12–24 hours
- Strenuous exercise, saunas, or hot yoga for 48 hours
- Direct sun exposure (wear a hat if you must go outside)
- Alcohol and smoking (both impair healing)
Most patients return to desk work the next day. If you have an event or important meeting, schedule PRP at least three days in advance.
Week One: Managing the Healing Window
Days 2–7 are when your body begins the repair work. Visible improvements won’t show yet—this phase is about supporting the process.
- Redness fades within 2–4 days for most patients
- Flaking or dryness may appear as skin renews (do not exfoliate)
- Resume gentle cleansing with lukewarm water and a mild, fragrance-free cleanser
- Reintroduce moisturizer and mineral SPF 30+ after 48 hours
- Avoid active ingredients (retinol, acids, vitamin C) for 5–7 days
If you’re treating hair loss, you may notice increased shedding around day 5–10. This is expected—damaged hairs release to make room for new growth.
Weeks Two Through Twelve: When Results Emerge
PRP is not an instant fix. Collagen remodeling and cellular turnover take time.
Timeline for Visible Changes:
- Weeks 2–4: Skin texture feels smoother; pores may appear smaller
- Weeks 4–8: Fine lines soften; overall tone evens out
- Weeks 8–12: Continued improvement in firmness and hydration; for hair, new growth becomes visible
Most protocols call for 3–4 sessions spaced 4–6 weeks apart, followed by maintenance treatments every 6–12 months. Your RN will tailor the schedule based on your response and goals.
Best Practices for Loveland Patients: Maximizing Your Investment
Living in Northern Colorado means sun, wind, and altitude—all factors that affect healing and results.
- Sun protection is non-negotiable. UV exposure degrades collagen faster than PRP can rebuild it. Reapply mineral sunscreen every two hours outdoors.
- Hydration matters at elevation. Drink more water than you think you need.
- Support your skin barrier. Use ceramide-rich moisturizers and avoid harsh cleansers.
- Pair PRP with professional-grade skincare. Ask your RN which serums complement your treatment plan.
- Be patient. Three months is the standard window for full results. Early stoppers miss the payoff.
Explore our full menu of regenerative and rejuvenating treatments on our services page to see how PRP fits into a comprehensive plan.
Frequently Asked Questions
How much does Platelet Rich Plasma cost per session?
PRP pricing typically ranges from $600–$1,200 per session depending on treatment area and technique (injection vs. microneedling). Package pricing for multi-session series often reduces the per-treatment cost. We provide transparent pricing during your consultation so you can plan accordingly.
Is there anyone who shouldn’t get PRP?
Yes. PRP is not recommended if you have active skin infections, certain blood disorders (like thrombocytopenia), are pregnant or nursing, or are on blood thinners you cannot pause. Your medical history review will flag any concerns before we proceed.
Can I combine PRP with other treatments?
Often, yes—but timing matters. PRP pairs well with microneedling, laser resurfacing, and certain injectables, but treatments must be sequenced correctly to avoid interference or excess inflammation. Your RN will map out a safe, effective combination plan if multiple modalities suit your goals.
Ready to Start Your PRP Journey?
Platelet Rich Plasma works best when expectations are clear and aftercare is diligent. Our RN-led team at 18 Spa guides you through every phase—from your first consultation to your final follow-up—so you feel informed, supported, and confident in your decision.
If you’re curious whether PRP is right for your skin or hair concerns, let’s talk. Book your consultation and we’ll build a plan that fits your goals, your schedule, and your life in Loveland.
